Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 19/20 | 0.57 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.57 |
| ▸ | CALCA | P06881 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036256 | 0.92 | CALCA (0.63) | CALCRLRAMP1CALCA | |
| SCHEMBL14036378 | 0.91 | CALCRL (0.57) | CALCRLRAMP1CALCA | |
| SCHEMBL3519017 | 0.91 | CALCRL (0.58) | CALCRLRAMP1CALCA | |
| SCHEMBL3519015 | 0.91 | CALCRL (0.58) | CALCRLRAMP1CALCA | |
| SCHEMBL3520488 | 0.90 | CALCRL (0.58) | CALCRLRAMP1CALCA | |
| SCHEMBL3520483 | 0.90 | CALCRL (0.58) | CALCRLRAMP1CALCA | |
| SCHEMBL2165660 | 0.90 | CALCRL (0.62) | CALCRLRAMP1CALCA | |
| SCHEMBL2165652 | 0.90 | CALCRL (0.62) | CALCRLRAMP1CALCA | |
| SCHEMBL14036218 | 0.89 | CALCRL (0.59) | CALCRLRAMP1CALCA | |
| SCHEMBL2166457 | 0.87 | CALCRL (0.62) | CALCRLRAMP1CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992349-B1 | CGRP antagonists, their preparation and use as a medicament | BOEHRINGER INGELHEIM INT (DE) | 2013-07-31 | — | — | EP | disclosed |
| EP-1992349-A1 | CGRP antagonists, their preparation and use as a medicament | Boehringer Ingelheim International GmbH (DE) | 2008-11-19 | — | — | EP | disclosed |