Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20251142 | 0.88 | KCNA5 (0.46) | KCNA5KDM4AACHEBCHETRPV1 | |
| SCHEMBL13091273 | 0.86 | GLS (0.44) | KCNA5KDM4ATRPV1 | |
| SCHEMBL23833321 | 0.84 | KCNA5 (0.43) | KCNA5KDM4ATRPV1 | |
| SCHEMBL30193003 | 0.84 | KCNA5 (0.43) | KCNA5KDM4ATRPV1 | |
| SCHEMBL23833131 | 0.84 | TRPV1 (0.52) | KCNA5KDM4ATRPV1 | |
| SCHEMBL30193479 | 0.84 | TRPV1 (0.52) | KCNA5KDM4ATRPV1 | |
| SCHEMBL5015072 | 0.82 | NPC1 (0.54) | KCNA5KDM4A | |
| SCHEMBL6921464 | 0.80 | IDO1 (0.50) | KCNA5KDM4A | |
| SCHEMBL8011978 | 0.80 | AAK1 (0.47) | KCNA5KDM4A | |
| SCHEMBL654820 | 0.80 | KDM4A (0.45) | KCNA5KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |