Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015072 | 0.81 | NPC1 (0.54) | KDM4AKCNA5LMNAL3MBTL1NQO2 | |
| SCHEMBL5015064 | 0.81 | KCNA5 (0.46) | KDM4AKCNA5KDM4ELMNATDP1 | |
| SCHEMBL5460255 | 0.81 | EPHX2 (0.42) | KDM4AKCNA5KDM4ELMNATDP1 | |
| SCHEMBL25213561 | 0.80 | KDM4A (0.39) | KDM4AKCNA5KDM4ELMNATDP1 | |
| SCHEMBL15171404 | 0.80 | NPC1 (0.52) | KDM4AKCNA5KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL13761066 | 0.79 | KDM4A (0.45) | KDM4AKCNA5KDM4ELMNATDP1 | |
| SCHEMBL6921464 | 0.79 | IDO1 (0.50) | KDM4AKCNA5KDM4EALDH1A1MAPT | |
| SCHEMBL654820 | 0.79 | KDM4A (0.45) | KDM4AKCNA5KDM4EL3MBTL1NQO2 | |
| SCHEMBL8011978 | 0.79 | AAK1 (0.47) | KDM4AKCNA5L3MBTL1NQO2HDAC10 | |
| SCHEMBL31142972 | 0.79 | AAK1 (0.47) | KDM4AKCNA5L3MBTL1NQO2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |