Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015113 | 0.91 | KCNA5 (0.42) | KCNA5KDM4AKDM4ELMNAAAK1 | |
| SCHEMBL5739222 | 0.81 | ALDH1A1 (0.40) | KCNA5KDM4AKDM4ELMNAAAK1 | |
| SCHEMBL14036623 | 0.81 | KDM4A (0.44) | KCNA5KDM4AKDM4ELMNAALDH1A1 | |
| SCHEMBL27723354 | 0.80 | KCNA5 (0.39) | KCNA5KDM4AKDM4ELMNAAAK1 | |
| SCHEMBL5460255 | 0.80 | EPHX2 (0.42) | KCNA5KDM4AKDM4ELMNAALDH1A1 | |
| SCHEMBL14036620 | 0.79 | KCNA5 (0.45) | KCNA5KDM4ATRPV1 | |
| SCHEMBL13761066 | 0.78 | KDM4A (0.45) | KCNA5KDM4AKDM4ELMNAALDH1A1 | |
| SCHEMBL5015072 | 0.78 | NPC1 (0.54) | KCNA5KDM4ALMNAALDH1A1MAPT | |
| SCHEMBL27643741 | 0.77 | KCNA5 (0.39) | KCNA5KDM4AKDM4ELMNAAAK1 | |
| SCHEMBL15171404 | 0.77 | NPC1 (0.52) | KCNA5KDM4AKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |