Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630869 | 0.79 | MEN1 (0.62) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL29114695 | 0.74 | TSHR (0.66) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL2471248 | 0.74 | KDM1A (0.59) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL5798027 | 0.74 | KDM4E (0.56) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL23124616 | 0.73 | KDM4E (0.57) | MEN1KMT2AKDM4EGAAHTT | |
| Hydrochloric Acid SCHEMBL31580079 | 0.73 | TSHR (0.64) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL14036538 | 0.72 | KDM1A (0.57) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL695065 | 0.71 | MEN1 (0.68) | MEN1KMT2AGAAALDH1A1POLB | |
| SCHEMBL696258 | 0.71 | BCHE (0.68) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL16767556 | 0.71 | MEN1 (0.56) | MEN1KMT2AKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |