Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036914 | 0.91 | CYP1A2 (0.40) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL5015576 | 0.85 | LMNA (0.48) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL11099078 | 0.79 | LMNA (0.51) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL11397970 | 0.78 | SMN1; SMN2 (0.51) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL14036796 | 0.78 | SMN1; SMN2 (0.42) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL11399957 | 0.77 | SMN1; SMN2 (0.52) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL5017332 | 0.76 | LMNA (0.49) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL11398926 | 0.75 | LMNA (0.57) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL10479183 | 0.73 | LMNA (0.40) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL11300897 | 0.72 | LMNA (0.54) | LMNACYP1A2KDM4EGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465876-B1 | LONG CHAIN FATTY ALCOHOL SUBSTITUENTS IN ANTINEOPLASTIC AGENTS | PFAENDLER HANS RUDOLF (DE) | 2008-11-05 | — | — | EP | disclosed |