Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12511127 | 0.84 | DPP4 (0.34) | DPP4DPP7 | |
| SCHEMBL9712679 | 0.83 | KDM4E (0.35) | KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL14457366 | 0.79 | KDM4E (0.33) | KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL18862664 | 0.77 | CNR2 (0.37) | — | |
| SCHEMBL21233435 | 0.77 | DPP4 (0.32) | DPP4DPP7 | |
| SCHEMBL4079377 | 0.77 | KDM4E (0.32) | KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL2678474 | 0.77 | KDM4E (0.44) | KDM4ENPC1RAB9A | |
| SCHEMBL12299810 | 0.76 | DPP4 (0.32) | DPP4DPP7 | |
| SCHEMBL18643327 | 0.74 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL25419135 | 0.73 | KDM4E (0.37) | KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141011-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |