Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079377 | 0.82 | KDM4E (0.32) | KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL14037256 | 0.79 | KDM4E (0.35) | KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL9712679 | 0.79 | KDM4E (0.35) | KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL25419135 | 0.79 | KDM4E (0.37) | KDM4ENPC1RAB9A | |
| SCHEMBL1445215 | 0.76 | ALOX5 (0.34) | — | |
| SCHEMBL18862664 | 0.67 | CNR2 (0.37) | — | |
| Hydrazinecarboxamide SCHEMBL22471913 | 0.63 | LMNA (0.38) | KDM4ENPC1RAB9A | |
| SCHEMBL12511127 | 0.61 | DPP4 (0.34) | — | |
| SCHEMBL14399861 | 0.61 | TSHR (0.30) | — | |
| SCHEMBL20832857 | 0.60 | TSHR (0.37) | KDM4ENPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005721-A1 | INDOLIZINE INHIBITORS OF 5-LIPOXYGENASE | PANMIRA PHARMACEUTICALS, LLC (US) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005721-A1 | INDOLIZINE INHIBITORS OF 5-LIPOXYGENASE | ALOX5, ALOX15, ALOX15B | KDM4E 1696/4885NPC1 2214/4885RAB9A 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.