⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250367 | 0.76 | TAAR1 (0.46) | — | |
| SCHEMBL892031 | 0.74 | — | — | |
| SCHEMBL4263926 | 0.74 | — | — | |
| SCHEMBL1533571 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL29101971 | 0.74 | TAAR1 (0.45) | — | |
| SCHEMBL2059056 | 0.74 | — | — | |
| SCHEMBL22686237 | 0.71 | TAAR1 (0.58) | — | |
| SCHEMBL1523197 | 0.70 | — | — | |
| SCHEMBL14037442 | 0.69 | TAAR1 (0.41) | — | |
| SCHEMBL5746177 | 0.69 | CYP2C19 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126338-A | Preparation method and application of ZIFs material with cage-shaped finite structure and hydrogen bonding action site | 太原理工大学 | 2024-06-04 | — | — | CN | claimed |
| CN-113271939-B | Imidazole tetrazine compounds | 伊利诺伊大学董事会 | 2025-03-07 | — | — | CN | disclosed |
| US-20250066371-A1 | FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | MODIFI BIOSCIENCES, INC. | 2025-02-27 | — | — | US | disclosed |
| US-12234240-B2 | Substituted imidazo[5,1-d][1,2,3,5]tetrazines for the treatment of cancer | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-02-25 | — | — | US | disclosed |
| CN-118126338-A | Preparation method and application of ZIFs material with cage-shaped finite structure and hydrogen bonding action site | 太原理工大学 | 2024-06-04 | — | — | CN | disclosed |
| US-20240124462-A9 | SUBSTITUTED IMIDAZO[5,1-d][1,2,3,5]TETRAZINES FOR THE TREATMENT OF CANCER | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-04-18 | — | — | US | disclosed |
| US-20240059680-A1 | N-(2,3-DIHYDRO-1,4-BENZOXAZIN-4-YL)-3-ISOPROPYL-7-(2,3,5-TRIFLUOROPHENYL)BENZO-THIOPHENE-2-CARBOXAMIDE DERIVATIVES AND SIMILAR COMPOUNDS FOR THE TREATMENT OF HEARTWORM INFECTIONS | ELANCO TIERGESUNDHEIT AG (CH) | 2024-02-22 | — | — | US | disclosed |
| CN-116685584-A | N- (2, 3-dihydro-1, 4-benzoxazin-4-yl) -3-isopropyl-7- (2, 3, 5-trifluorophenyl) benzothiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections | 礼蓝动物保健有限公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20230183252-A1 | SUBSTITUTED IMIDAZO[5,1-d][1,2,3,5]TETRAZINES FOR THE TREATMENT OF CANCER | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230183252-A1 | SUBSTITUTED IMIDAZO[5,1-d][1,2,3,5]TETRAZINES FOR THE TREATMENT OF CANCER | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-06-15 | — | — | US | disclosed |
| US-20210315886-A1 | IMIDAZOTETRAZINE COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-10-14 | — | — | US | disclosed |
| CN-113271939-A | Imidazole tetrazine compounds | 伊利诺伊大学董事会 | 2021-08-17 | — | — | CN | disclosed |
| EP-3833342-A1 | IMIDAZOTETRAZINE COMPOUNDS | The Board of Trustees of the University of Illinois (US) | 2021-06-16 | — | — | EP | disclosed |
| US-20210002286-A1 | IMIDAZOTETRAZINE COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-01-07 | — | — | US | disclosed |
| WO-2020033880-A1 | IMIDAZOTETRAZINE COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-02-13 | — | — | WO | disclosed |
| EP-1744720-B1 | KERATIN DYEING COMPOSITIONS CONTAINING bicyclic 5-5 heteroaromatic compounds | PROCTER & GAMBLE (US) | 2008-11-26 | — | — | EP | disclosed |
| US-7255835-B2 | Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-08-14 | — | — | US | disclosed |
| US-7255835-B2 | Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-08-14 | — | — | US | disclosed |
| US-7229480-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-12 | — | — | US | disclosed |
| US-7229480-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-12 | — | — | US | disclosed |