SCHEMBL250367

SCHEMBL250367

O=[N+]([O-])c1nc[nH]c1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.46
LMNA P02545 3/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 5/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 2/20 0.40
NAMPT P43490 1/20 0.40
XDH P47989 1/20 0.40
KMT2A Q03164 2/20 0.36
PARP1 P09874 1/20 0.36
MEN1 O00255 1/20 0.36
KDM4E B2RXH2 1/20 0.34
HBB P68871 2/20 0.33
BLM P54132 2/20 0.33
GMNN O75496 1/20 0.33
TP53 P04637 1/20 0.33
PGR P06401 1/20 0.33
SLC6A4 P31645 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29101971 0.98 TAAR1 (0.45) TAAR1LMNAPOLBMAPTTDP1
SCHEMBL1523197 0.76
SCHEMBL1533571 0.76
SCHEMBL3605224 0.76
SCHEMBL9669161 0.76
SCHEMBL4263926 0.76
SCHEMBL2059056 0.76
SCHEMBL4299008 0.76
SCHEMBL755097 0.76
SCHEMBL9044558 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4308181-B1 SUTURES UNIV BELFAST (GB) 2025-11-19 EP claimed
CN-119978317-A Epoxy resin intrinsic flame retardant material cured by phosphorus-containing imidazole curing agent and preparation method thereof 广东精英高新材料股份有限公司 2025-05-13 CN claimed
CN-114395390-B Fluorescence array sensor based on aggregation-induced emission type metal organic framework, and preparation method and application thereof 南京理工大学 2023-12-15 CN claimed
CN-111039977-B Phosphorylylation reagent and application thereof in oligonucleotide synthesis 广州同隽医药科技有限公司 2022-11-08 CN claimed
CN-114395390-A Fluorescence array sensor based on aggregation-induced emission type metal organic framework and preparation method and application thereof 南京理工大学 2022-04-26 CN claimed
CN-109796411-B Method for preparing 4, 5-dinitroimidazole by using microchannel reactor 南京理工大学 2022-01-14 CN claimed
CN-107365439-B Novel chloroprene rubber vulcanization method 华南理工大学 2020-02-18 CN claimed
CN-102574250-A Soldering process using electrodeposited indium and/or gallium, and article comprising an intermediate layer with indium and/or gallium ASTRON ADVANCED MATERIALS LTD 2012-07-11 CN claimed
US-4300962-A Ammonium nitrate explosive systems THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-11-17 US claimed
JP-63310873-A None JP disclosed
US-12637415-B2 Lyophilized composition comprising (s)-isopropyl 2-((s)-2-acetamido-3-(1H-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate for intravenous administration and the use thereof DRACEN PHARMACEUTICALS, INC. (US) 2026-05-26 US disclosed
US-12616679-B2 Lyophilized composition comprising (s)-isopropyl 2-((s)-2-acetamido-3-(1H-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate for subcutaneous administration and the use thereof DRACEN PHARMACEUTICALS, INC. (US) 2026-05-05 US disclosed
US-12605472-B2 Radiolabeling of anti-CD45 immunoglobulin and methods of use thereof ACTINIUM PHARMACEUTICALS, INC. (US) 2026-04-21 US disclosed
EP-4089823-B1 SEPARATOR, ELECTRICAL APPARATUS CONTAINING SUCH SEPARATOR, AND PREPARATION METHOD THEREOF CONTEMPORARY AMPEREX TECHNOLOGY HONG KONG LTD (HK) 2026-04-01 EP disclosed
US-5256792-A Explosives and gun propellants; thermally stable, insensitive to shock THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1993-10-26 US disclosed
EP-0290991-B1 PROCESS FOR THE PRODUCTION OF PYRAZOLES BASF Aktiengesellschaft (DE) 1992-07-29 EP disclosed
JP-S63310873-A 4,5-DINITROIMIDAZOLE DERIVATIVE TAIHO YAKUHIN KOGYO KK 1988-12-19 JP disclosed
EP-0290991-A1 Process for the production of pyrazoles BASF Aktiengesellschaft (DE) 1988-11-17 EP disclosed
US-4430445-A POLYAMIDINE HOHO- AND COPOLYMERS; OXIDATION RESISTANCE; METAL EXTRACTION; POLYEPOXIDE CURING AGENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-02-07 US disclosed
US-4300962-A Ammonium nitrate explosive systems THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616679-B2 Lyophilized composition comprising (s)-isopropyl 2-((s)-2-acetamido-3-(1H-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate for subcutaneous administration and the use thereof GLUL, QPCT, QPCTL TAAR1 4604/4885LMNA 3930/4885POLB 557/4885
US-12605472-B2 Radiolabeling of anti-CD45 immunoglobulin and methods of use thereof HBZ, CD47, HBB TAAR1 4350/4885LMNA 2908/4885POLB 636/4885
US-12637415-B2 Lyophilized composition comprising (s)-isopropyl 2-((s)-2-acetamido-3-(1H-indol-3-yl)propanamido)-6-diazo-5-oxohexanoate for intravenous administration and the use thereof GLS, GLUL, GLS2 TAAR1 4542/4885LMNA 3864/4885POLB 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.