SCHEMBL14038451

SCHEMBL14038451

C[C@H]1CN2CCCC2CN1C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(F)c(Cl)c3)c2C1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRKCB P05771 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14038453 0.92 PRKCB (0.73) PRKCB
SCHEMBL6375894 0.86 PRKCB (0.73) PRKCB
SCHEMBL598986 0.84 PRKCB (1.00) PRKCB
SCHEMBL6375929 0.79 PRKCB (0.72) PRKCB
SCHEMBL14038471 0.79 PRKCB (0.72) PRKCB
SCHEMBL6468537 0.78 PRKCB (0.73) PRKCB
SCHEMBL596914 0.77 PRKCB (1.00) PRKCB
SCHEMBL18155598 0.77 PRKCB (0.73) PRKCB
SCHEMBL601644 0.76 PRKCB (1.00) PRKCB
SCHEMBL6377156 0.75 PRKCB (0.73) PRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008125945-A2 3-AMIDO-PYRROLO [3, 4-C] PYRAZOLE-5 (1H, 4H, 6H) CARBALDEHYDE DERIVATIVES AS INHIBITORS OF PROTEIN KINASE C PFIZER INC. (US) 2008-10-23 WO disclosed