Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 19/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.54 |
| ▸ | TCF7 | P36402 | 2/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | TCF4 | P15884 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749233 | 0.94 | CLPP (0.55) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749201 | 0.93 | CLPP (0.54) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749225 | 0.92 | CLPP (0.66) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747777 | 0.92 | CLPP (0.56) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL746192 | 0.92 | CLPP (0.66) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749182 | 0.91 | CTNNB1 (0.67) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL750136 | 0.91 | CLPP (0.56) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747283 | 0.90 | CLPP (0.67) | CLPPCTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749222 | 0.88 | CLPP (0.57) | CLPP | |
| SCHEMBL747780 | 0.88 | CLPP (0.51) | CLPPCTNNB1TCF7BCL9TCF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318738-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-11-27 | — | — | US | disclosed |