Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 18/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | TCF7 | P36402 | 2/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | TCF4 | P15884 | 1/20 | 0.39 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750241 | 0.93 | CYP3A4 (0.42) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747745 | 0.90 | CYP3A4 (0.42) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747254 | 0.88 | CYP3A4 (0.45) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL747158 | 0.88 | CYP3A4 (0.45) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL10225947 | 0.88 | CYP3A4 (0.45) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL751496 | 0.88 | CYP3A4 (0.46) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749333 | 0.86 | CTNNB1 (0.43) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749814 | 0.86 | CYP3A4 (0.47) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL749902 | 0.86 | ALDH1A1 (0.48) | CYP3A4CTNNB1TCF7BCL9TCF4 | |
| SCHEMBL10226487 | 0.86 | CYP3A4 (0.45) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318738-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-11-27 | — | — | US | disclosed |
| US-8318738-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-11-27 | — | — | US | disclosed |