Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 17/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 14/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 14/20 | 0.48 |
| ▸ | SRC | P12931 | 12/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111814 | 0.88 | FGFR1 (0.46) | FGFR1PDGFRBPDGFRASRCEGFR | |
| SCHEMBL5114782 | 0.87 | FGFR1 (0.45) | FGFR1PDGFRBPDGFRASRCEGFR | |
| SCHEMBL5107303 | 0.81 | MAPK14 (0.57) | MAPK14MAPK8PRKD3MAPK1 | |
| SCHEMBL29594951 | 0.81 | MAPK14 (0.57) | MAPK14MAPK8PRKD3MAPK1 | |
| SCHEMBL13530692 | 0.71 | FGFR1 (0.45) | FGFR1PDGFRBPDGFRASRCEGFR | |
| SCHEMBL5122174 | 0.66 | MAPK8 (0.43) | MAPK14MAPK8 | |
| SCHEMBL25222319 | 0.65 | MAPK8 (0.42) | MAPK14MAPK8 | |
| SCHEMBL29536776 | 0.65 | MAPK8 (0.42) | MAPK14MAPK8 | |
| SCHEMBL6073910 | 0.65 | FGFR1 (0.50) | FGFR1PDGFRBPDGFRASRCEGFR | |
| SCHEMBL8129964 | 0.65 | FGFR1 (1.00) | FGFR1PDGFRBPDGFRASRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449581-B2 | 6-Substituted pyrido-pyrimidines | POCHE PALO ALTO LLC (US) | 2008-11-11 | — | — | US | disclosed |