Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 18/20 | 0.45 |
| ▸ | SRC | P12931 | 11/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 10/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13476071 | 0.81 | SYK (0.47) | HTTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL1225015 | 0.79 | AURKA (0.37) | EGFRKDM4EGAA | |
| SCHEMBL13530680 | 0.79 | AURKA (0.43) | GAAHSD17B10MAPK1 | |
| SCHEMBL13530696 | 0.77 | AURKA (0.45) | NPC1ALDH1A1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13383587 | 0.76 | AURKA (0.37) | ALDH1A1MAPK1 | |
| SCHEMBL13530676 | 0.75 | RAB9A (0.51) | HTTKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL13383572 | 0.75 | SMN1; SMN2 (0.43) | KDM4EALDH1A1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL13383266 | 0.75 | ADORA3 (0.40) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL1270948 | 0.75 | SMN1; SMN2 (0.50) | FGFR1SRCHTTFGFR3NPC1 | |
| SCHEMBL13530861 | 0.74 | AURKA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9204653-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-9204653-B2 | 5-fluoro pyrimidine derivatives | DOW AGROSCIENCES LLC (US) | 2015-12-08 | — | — | US | disclosed |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | disclosed |
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022538-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | FGFR1 2405/4885SRC 1727/4885PDGFRB 1313/4885 |
| US-20140024616-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES | DPYD, DPM1, DDX5 | FGFR1 2405/4885SRC 1727/4885PDGFRB 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.