Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.52 |
| ▸ | MMP9 | P14780 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31630104 | 1.00 | MMP2 (0.52) | MMP2MMP9TSHRSMN1; SMN2CA1 | |
| SCHEMBL31630053 | 1.00 | MMP2 (0.52) | MMP2MMP9TSHRSMN1; SMN2CA1 | |
| SCHEMBL31630207 | 0.97 | MMP2 (0.49) | MMP2MMP9TSHRSMN1; SMN2CA1 | |
| SCHEMBL31630110 | 0.97 | MMP2 (0.49) | MMP2MMP9TSHRSMN1; SMN2CA1 | |
| SCHEMBL31630255 | 0.84 | MMP2 (0.74) | MMP2MMP9TSHRSMN1; SMN2MEN1 | |
| SCHEMBL31630491 | 0.84 | MMP2 (0.74) | MMP2MMP9TSHRSMN1; SMN2MEN1 | |
| SCHEMBL31630187 | 0.84 | MMP2 (0.59) | MMP2MMP9TSHRCA1CA2 | |
| SCHEMBL14132802 | 0.84 | MMP2 (0.49) | MMP2MMP9SMN1; SMN2ALDH1A1MMP3 | |
| SCHEMBL13691537 | 0.82 | CA1 (0.52) | MMP2MMP9TSHRSMN1; SMN2CA1 | |
| SCHEMBL31630241 | 0.81 | MMP2 (0.55) | MMP2MMP9TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124698-A1 | ARYL SULFONE AND SULFANONE DERIVATIVES AS OREXIN RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-19 | — | — | WO | disclosed |
| US-8324207-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-04 | — | — | US | disclosed |
| US-8318733-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-11-27 | — | — | US | disclosed |