Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832147 | 0.94 | F10 (0.63) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5723861 | 0.83 | F10 (0.62) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14039717 | 0.82 | F10 (0.73) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8467077 | 0.80 | F10 (0.74) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8450262 | 0.80 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3832364 | 0.80 | F10 (0.67) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13726599 | 0.78 | F10 (0.73) | F10FPR1FPR2 | |
| SCHEMBL3828794 | 0.78 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3835399 | 0.78 | F10 (0.86) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3834666 | 0.78 | F10 (0.86) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | WARNER-LAMBERT COMPANY LLC | 2008-11-20 | — | — | US | disclosed |
| US-7407972-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | PFIZER INC. (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | TFPI, F11, F2 | F10 11/4885F2 3/4885PRSS1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.