Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.64 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834633 | 0.93 | F10 (0.74) | F10 | |
| SCHEMBL8467077 | 0.93 | F10 (0.74) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8467091 | 0.92 | F10 (0.76) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3833827 | 0.87 | F10 (0.85) | F10 | |
| SCHEMBL3833832 | 0.87 | F10 (0.85) | F10 | |
| SCHEMBL3829980 | 0.85 | F10 (0.87) | F10 | |
| SCHEMBL8450077 | 0.85 | F10 (0.87) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8459315 | 0.83 | F10 (0.61) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14039569 | 0.82 | F10 (0.73) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3834651 | 0.82 | F10 (0.85) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | WARNER-LAMBERT COMPANY LLC | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | TFPI, F11, F2 | F10 11/4885F2 3/4885PRSS1 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.