Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13725870 | 0.89 | F10 (0.62) | F10KLKB1 | |
| SCHEMBL3833337 | 0.83 | F10 (0.71) | F10KLKB1 | |
| SCHEMBL8448048 | 0.79 | F10 (0.53) | F10KLKB1CYP1A2POLBCYP3A4 | |
| SCHEMBL3833790 | 0.79 | F10 (0.59) | F10KLKB1 | |
| SCHEMBL3829836 | 0.76 | F10 (0.58) | F10KLKB1POLB | |
| SCHEMBL76138 | 0.74 | F10 (0.79) | F10 | |
| SCHEMBL3834666 | 0.74 | F10 (0.86) | F10KLKB1CYP1A2POLBCYP3A4 | |
| SCHEMBL3835399 | 0.74 | F10 (0.86) | F10KLKB1CYP1A2POLBCYP3A4 | |
| SCHEMBL14039720 | 0.73 | F10 (0.73) | F10KLKB1 | |
| SCHEMBL3828763 | 0.73 | F10 (0.49) | F10KLKB1CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | WARNER-LAMBERT COMPANY LLC | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | TFPI, F11, F2 | F10 11/4885KLKB1 116/4885CYP1A2 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.