Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808850 | 0.87 | KMT2A (0.39) | KMT2AMEN1POLBTSHRHSD17B10 | |
| SCHEMBL1398482 | 0.83 | CYP11B2 (0.37) | KMT2AMEN1POLBTSHRHSD17B10 | |
| SCHEMBL1398630 | 0.79 | AR (0.45) | KMT2AMEN1POLBTSHRHSD17B10 | |
| SCHEMBL12809019 | 0.78 | KMT2A (0.37) | KMT2AMEN1POLBTSHRHSD17B10 | |
| SCHEMBL1398658 | 0.74 | CYP11B2 (0.36) | KMT2AMEN1NPC1LMNAALDH1A1 | |
| SCHEMBL12809018 | 0.73 | MEN1 (0.39) | KMT2AMEN1POLBTSHRHSD17B10 | |
| SCHEMBL1398522 | 0.72 | MEN1 (0.38) | KMT2AMEN1POLBTSHRHSD17B10 | |
| SCHEMBL15999091 | 0.71 | KDM4E (0.39) | POLBHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL15999082 | 0.70 | CYP11B2 (0.53) | KMT2AMEN1TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL1398518 | 0.70 | MAPT (0.39) | KMT2AMEN1HSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128951-A1 | OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE (S1P) AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |