Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593130 | 0.95 | TLR4 (0.32) | OPRM1OPRK1OPRL1HSD11B1 | |
| SCHEMBL4593075 | 0.95 | TLR4 (0.32) | OPRM1OPRK1OPRL1HSD11B1 | |
| SCHEMBL14039685 | 0.90 | OPRM1 (0.34) | HTR1AADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL14113085 | 0.86 | OPRM1 (0.34) | HTR1AADRA1DADRA1AADRA1BOPRM1 | |
| SCHEMBL14154517 | 0.83 | GRIN1 (0.35) | HTR1AADRA1DADRA1AADRA1BGRIN1 | |
| SCHEMBL14039709 | 0.78 | OPRM1 (0.53) | HTR1AOPRM1OPRK1OPRL1 | |
| SCHEMBL14154623 | 0.77 | MAOB (0.33) | HSD11B1MAOB | |
| SCHEMBL14039841 | 0.76 | TLR4 (0.32) | OPRM1OPRK1OPRL1 | |
| SCHEMBL14154634 | 0.74 | OPRM1 (0.41) | OPRM1OPRK1OPRL1 | |
| SCHEMBL14039712 | 0.74 | TLR4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776438-B1 | LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2008-10-08 | — | — | EP | disclosed |
| US-20080167482-A1 | mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080167482-A1 | mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |