Benzophenone

Benzophenone

SCHEMBL1404019

O=C(c1ccccc1)c1ccccc1.[F-].[H+]

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.88
SRD5A2 P31213 2/20 0.70
TDP1 Q9NUW8 2/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
ATM Q13315 1/20 0.70
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
RAB9A P51151 3/20 0.58
MAPT P10636 3/20 0.58
LMNA P02545 1/20 0.58
MAPK13 O15264 1/20 0.58
MAPK12 P53778 1/20 0.58
MAPK11 Q15759 1/20 0.58
MAPK14 Q16539 1/20 0.58
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
TSHR P16473 2/20 0.58
DAO P14920 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
AKR1C3 P42330 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL27498689 0.97 ALDH1A1 (0.93) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL1404124 0.94 ALDH1A1 (0.88) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL28180817 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL30536983 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL17745 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL28491203 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL1074283 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL30537001 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL6061130 0.94 ALDH1A1 (1.00) ALDH1A1SRD5A2TDP1L3MBTL1ATM
Benzophenone SCHEMBL23175179 0.90 ALDH1A1 (0.93) ALDH1A1SRD5A2TDP1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291415-B1 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES BRIDGESTONE CORP (JP) 2016-07-20 EP disclosed
US-8664343-B2 Catalysts for preparing cis 1,4-polydienes BRIDGESTONE CORPORATION (JP) 2014-03-04 US disclosed
US-20110184137-A1 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
EP-2291415-A2 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES Bridgestone Corporation (JP) 2011-03-09 EP disclosed
US-7820580-B2 Nickel-based catalysts for preparing high cis 1,4-polydienes BRIDGESTONE CORPORATION (JP) 2010-10-26 US disclosed
WO-2009155170-A2 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2009-12-23 WO disclosed
US-20090143551-A1 NICKEL-BASED CATALYSTS FOR PREPARING HIGH CIS 1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2009-06-04 US disclosed
EP-1590382-B1 IMPROVED TERMINATION AND REDUCED GEL IN HIGH CIS POLYBUTADIENE FIRESTONE POLYMERS LLC (US) 2007-11-28 EP disclosed
EP-1590382-A1 IMPROVED TERMINATION AND REDUCED GEL IN HIGH CIS POLYBUTADIENE Firestone Polymers, LLC (US) 2005-11-02 EP disclosed
WO-2004072132-A1 IMPROVED TERMINATION AND REDUCED GEL IN HIGH CIS POLYBUTADIENE FIRESTONE POLYMERS, LLC (US) 2004-08-26 WO disclosed
US-6596825-B1 Process for forming a high-cis polydiene. The process includes catalyzing a diene polymerization, and terminating the polymerization with an amine-water termination mixture, preferably a TMEDA-water termination mixture. The catalyst FIRESTONE POLYMERS, LLC 2003-07-22 US disclosed
EP-0980878-A1 Molecular weight regulation of cis-1,4-polybutadiene using carboxylates Bridgestone Corporation (JP) 2000-02-23 EP disclosed
US-5955553-A Molecular weight regulation of cis-1,4-polybutadiene using carboxylates BRIDGESTONE CORPORATION (US) 1999-09-21 US disclosed
US-5698643-A USING COORDINATION CATALYST; TIRES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-12-16 US disclosed
US-4983695-A Catalysis with nickel carboxylate, trialkylaluminum, and hydrogen fluoride ether complex THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-01-08 US disclosed
EP-0093075-B1 PREPARATION OF HIGH CIS-1,4-POLYBUTADIENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-12-30 EP disclosed
EP-0093075-A1 Preparation of high cis-1,4-polybutadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-02 EP disclosed
EP-0093074-A1 Controlling the molecular weight of polybutadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-02 EP disclosed
US-4383097-A USING NONCONJUGATED DIOLEFINS HAVING TRANS CONFIGURATION AND A CATALYST OF AN ORGANO ALUMINUM-NICKEL-FLUORINE COMPLEY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-05-10 US disclosed
US-3962375-A BUTADIENE POLYMERS, ORGANOALUMINUM-ORGANONICKEL-FLUORIDE CATALYST SYSTEM THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-06-08 US disclosed