Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451042 | 0.78 | HCAR2 (0.45) | ALDH1A1LMNAHSD17B10HCAR2NPSR1 | |
| SCHEMBL27528277 | 0.78 | — | — | |
| SCHEMBL3210776 | 0.78 | — | — | |
| SCHEMBL14269141 | 0.78 | — | — | |
| SCHEMBL23934647 | 0.77 | HCAR2 (0.37) | ALDH1A1LMNAHSD17B10HCAR2NPSR1 | |
| SCHEMBL8339071 | 0.77 | GAA (0.48) | ALDH1A1LMNAHSD17B10ALOX15MAPT | |
| SCHEMBL2117851 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL30605153 | 0.77 | HCAR2 (0.43) | ALDH1A1LMNAHSD17B10HCAR2NPSR1 | |
| SCHEMBL8642521 | 0.77 | — | — | |
| Alcohol SCHEMBL27866563 | 0.75 | HCAR2 (0.42) | ALDH1A1LMNAHSD17B10HCAR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620390-B1 | METHOD FOR THE SYNTHESIS OF 4-HYDROXYISOLEUCINE AND THE DERIVATIVES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2008-10-01 | — | — | EP | disclosed |
| US-7326805-B2 | Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof | MIOSKOWSKI CHARLES | 2008-02-05 | — | — | US | disclosed |
| US-7326805-B2 | Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof | MIOSKOWSKI CHARLES | 2008-02-05 | — | — | US | disclosed |
| US-20070043240-A1 | Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof | MIOSKOWSKI CHARLES | 2007-02-22 | — | — | US | disclosed |
| US-20070043240-A1 | Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof | MIOSKOWSKI CHARLES | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043240-A1 | Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof | IL4I1, CBR3, CBR1 | ALDH1A1 197/4885LMNA 3187/4885HSD17B10 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.