Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669305 | 0.80 | SLC6A4 (0.73) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL1047496 | 0.78 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL1077215 | 0.78 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL11847632 | 0.78 | GFER (0.48) | SLC6A4SLC6A2SLC6A3TAAR1MAOB | |
| SCHEMBL14044069 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3TAAR1 | |
| SCHEMBL14040458 | 0.76 | IDO1 (0.48) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL586783 | 0.76 | SLC6A2 (1.00) | SLC6A4SLC6A2SLC6A3TAAR1CYP2A6 | |
| SCHEMBL17045248 | 0.76 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3IDO1TAAR1 | |
| SCHEMBL22229845 | 0.76 | SLC6A2 (1.00) | SLC6A4SLC6A2SLC6A3TAAR1CYP2A6 | |
| SCHEMBL267030 | 0.76 | SLC6A2 (1.00) | SLC6A4SLC6A2SLC6A3TAAR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008125230-A2 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED AMINOHETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1982595-A1 | Insecticidal derivatives of substituted aminoheterocycles | Bayer CropScience AG (DE) | 2008-10-22 | — | — | EP | disclosed |