Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.61 |
| ▸ | PNMT | P11086 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267030 | 1.00 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| SCHEMBL586783 | 1.00 | SLC6A2 (1.00) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| Hydrochloric Acid SCHEMBL4519421 | 0.98 | SLC6A2 (0.95) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| Hydrochloric Acid SCHEMBL4363928 | 0.98 | SLC6A2 (0.95) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| Methane SCHEMBL19285556 | 0.98 | SLC6A2 (0.95) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| Hydrochloric Acid SCHEMBL3279916 | 0.98 | SLC6A2 (0.95) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| Hydrochloric Acid SCHEMBL1168686 | 0.98 | SLC6A2 (0.95) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| SCHEMBL9468251 | 0.94 | SLC6A2 (0.88) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| SCHEMBL20714984 | 0.94 | SLC6A2 (0.88) | SLC6A2SLC6A3SLC6A4TAAR1PNMT | |
| Sulfuric Acid SCHEMBL11130866 | 0.88 | SLC6A2 (0.78) | SLC6A2SLC6A3SLC6A4TAAR1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| WO-2021021893-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |
| US-20200231629-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231629-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | BET1, BACH1, POLL | SLC6A2 4825/4885SLC6A3 4853/4885SLC6A4 4873/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | SLC6A2 4865/4885SLC6A3 4845/4885SLC6A4 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.