Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.57 |
| ▸ | MMP9 | P14780 | 10/20 | 0.57 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.42 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703218 | 1.00 | MMP2 (0.57) | MMP2MMP9FPR1FPR2F10 | |
| SCHEMBL4700891 | 0.90 | MMP2 (0.72) | MMP2MMP9F10MMP3MMP13 | |
| SCHEMBL4700893 | 0.90 | MMP2 (0.72) | MMP2MMP9F10MMP3MMP13 | |
| SCHEMBL14040628 | 0.86 | MMP2 (0.53) | MMP2MMP9F10MMP3MMP13 | |
| SCHEMBL4701825 | 0.85 | F10 (0.54) | MMP2MMP9F10MMP1MMP3 | |
| SCHEMBL3109584 | 0.83 | MMP2 (0.74) | MMP2MMP9F10MMP3MMP13 | |
| SCHEMBL3109580 | 0.83 | MMP2 (0.74) | MMP2MMP9F10MMP3MMP13 | |
| SCHEMBL4702649 | 0.81 | MMP2 (0.58) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL4702643 | 0.81 | MMP2 (0.58) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL14604436 | 0.77 | F10 (0.71) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444202-B1 | NOVEL METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-10-15 | — | — | EP | disclosed |