Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16751015 | 1.00 | HTR2C (0.37) | HTR2CATMLRRK2CNR2KCNQ3 | |
| SCHEMBL13379873 | 1.00 | HTR2C (0.37) | HTR2CATMLRRK2CNR2KCNQ3 | |
| SCHEMBL18478944 | 1.00 | HTR2C (0.37) | HTR2CATMLRRK2CNR2KCNQ3 | |
| SCHEMBL25837324 | 0.82 | VNN1 (0.38) | ATM | |
| SCHEMBL25838114 | 0.82 | VNN1 (0.38) | ATM | |
| SCHEMBL5045861 | 0.82 | HTR2C (0.38) | HTR2CLRRK2CNR2KCNQ3KCNQ2 | |
| SCHEMBL5779223 | 0.82 | HTR2C (0.38) | HTR2CLRRK2CNR2KCNQ3KCNQ2 | |
| SCHEMBL4103692 | 0.82 | HTR2C (0.38) | HTR2CLRRK2CNR2KCNQ3KCNQ2 | |
| SCHEMBL15399575 | 0.82 | HTR2C (0.38) | HTR2CLRRK2CNR2KCNQ3KCNQ2 | |
| SCHEMBL16750117 | 0.79 | PIK3CD (0.42) | HTR2CLRRK2CNR2KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411940-B1 | BRIDGED PIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | MERCK & CO INC (US) | 2008-10-15 | — | — | EP | disclosed |