SCHEMBL1404061

SCHEMBL1404061

OCCCCCCCCCCCCN1CCOCC1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.61
ALDH1A1 P00352 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.56
KEAP1 Q14145 1/20 0.56
HPGD P15428 1/20 0.50
DUSP3 P51452 1/20 0.50
GLA P06280 1/20 0.45
PAOX Q6QHF9 1/20 0.45
GAA P10253 1/20 0.44
POLB P06746 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
KDM1A O60341 1/20 0.44
LMNA P02545 2/20 0.43
HTR7 P34969 2/20 0.43
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12014341 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL1404044 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL12014345 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL12014335 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL12014339 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL1403881 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL12014338 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL1403807 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL12014344 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD
SCHEMBL1404065 1.00 KDM4E (0.61) KDM4EALDH1A1SMN1; SMN2KEAP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP claimed
CN-100349851-C Method for producing acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
CN-100349854-C Method for producing (meth) acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US claimed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP claimed
US-10174349-B2 Recombinant cell producing 2-hydroxyisobutyric acid EVONIK ROEHM GMBH (DE) 2019-01-08 US disclosed
EP-2291530-B1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2018-12-26 EP disclosed
US-9176378-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-03 US disclosed
US-8728707-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-20 US disclosed
US-8728707-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-05-20 US disclosed
CN-101186603-B Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH 2014-01-08 CN disclosed
US-8568956-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-29 US disclosed
EP-2091906-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID Evonik Röhm GmbH (DE) 2009-08-26 EP disclosed
WO-2008061819-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed
WO-2008061821-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed
CN-101186568-A Process for preparing (meth)acrylic acid EVONIK ROEHM GMBH (DE) 2008-05-28 CN disclosed
CN-101186603-A Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH (DE) 2008-05-28 CN disclosed
US-6727232-B2 NEW SERIES OF NUCLEOSIDE PEPTIDE ANTIBIOTICS OF AA-896 WYETH HOLDINGS CORPORATION 2004-04-27 US disclosed
US-20030054983-A1 Antibiotics AA-896 AMERICAN CYANAMID COMPANY 2003-03-20 US disclosed
WO-2002085867-A1 ANTIBIOTICS AA-896 WYETH HOLDINGS CORPORATION (US) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030054983-A1 Antibiotics AA-896 Q6ZSR9, O60361, CYP2A6 KDM4E 3030/4885ALDH1A1 395/4885SMN1; SMN2 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.