Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 8/20 | 0.79 |
| ▸ | NOD2 | Q9HC29 | 8/20 | 0.79 |
| ▸ | ACVR1 | Q04771 | 6/20 | 0.79 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | BTK | Q06187 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 2/20 | 0.54 |
| ▸ | CCND1 | P24385 | 2/20 | 0.54 |
| ▸ | CCND2 | P30279 | 2/20 | 0.54 |
| ▸ | CCND3 | P30281 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20563559 | 0.88 | RIPK2 (1.00) | RIPK2NOD2ACVR1FGFR1SRC | |
| SCHEMBL5762208 | 0.87 | FGFR1 (0.75) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL5764524 | 0.85 | FGFR1 (0.72) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL5763095 | 0.81 | FGFR1 (0.70) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL29498196 | 0.81 | RIPK2 (1.00) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL5762020 | 0.81 | FGFR1 (0.68) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL5761780 | 0.79 | FGFR1 (0.70) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL10192790 | 0.79 | WEE1 (0.77) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL20563994 | 0.78 | RIPK2 (1.00) | RIPK2NOD2ACVR1FGFR1EGFR | |
| SCHEMBL5911585 | 0.77 | FGFR1 (0.83) | RIPK2NOD2ACVR1FGFR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |