Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.70 |
| ▸ | CA2 | P00918 | 16/20 | 0.70 |
| ▸ | CA12 | O43570 | 12/20 | 0.65 |
| ▸ | CA9 | Q16790 | 12/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5419122 | 0.91 | CA1 (0.58) | CA1CA2CA12CA9KDR | |
| SCHEMBL5183261 | 0.91 | CA1 (0.58) | CA1CA2CA12CA9KDR | |
| SCHEMBL6620145 | 0.88 | CA1 (0.54) | CA1CA2CA12CA9KDR | |
| SCHEMBL6620150 | 0.88 | CA1 (0.54) | CA1CA2CA12CA9KDR | |
| SCHEMBL15317870 | 0.87 | CA1 (0.66) | CA1CA2CA12CA9KDR | |
| SCHEMBL4664315 | 0.87 | CA1 (0.69) | CA1CA2CA12CA9KDR | |
| Hydrochloric Acid SCHEMBL5424689 | 0.87 | CA1 (0.53) | CA1CA2CA12CA9KDR | |
| SCHEMBL5427735 | 0.87 | CA1 (0.54) | CA1CA2CA12CA9KDR | |
| Gw275944X SCHEMBL5894233 | 0.87 | CA1 (0.69) | CA1CA2CA12CA9KDR | |
| SCHEMBL4663926 | 0.87 | CA1 (0.53) | CA1CA2CA12CA9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |