Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.54 |
| ▸ | CA2 | P00918 | 18/20 | 0.54 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 14/20 | 0.51 |
| ▸ | CA9 | Q16790 | 14/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620150 | 1.00 | CA1 (0.54) | CA1CA2EIF2AK2CA12CA9 | |
| Hydrochloric Acid SCHEMBL5424689 | 0.99 | CA1 (0.53) | CA1CA2EIF2AK2CA12CA9 | |
| Hydrochloric Acid SCHEMBL5170376 | 0.99 | CA1 (0.53) | CA1CA2EIF2AK2CA12CA9 | |
| SCHEMBL5419122 | 0.91 | CA1 (0.58) | CA1CA2EIF2AK2CA12CA9 | |
| SCHEMBL5183261 | 0.91 | CA1 (0.58) | CA1CA2EIF2AK2CA12CA9 | |
| Gw280670X SCHEMBL14040830 | 0.88 | CA1 (0.70) | CA1CA2EIF2AK2CA12CA9 | |
| SCHEMBL5434032 | 0.87 | CA1 (0.53) | CA1CA2EIF2AK2CA12CA9 | |
| SCHEMBL15317870 | 0.87 | CA1 (0.66) | CA1CA2EIF2AK2CA12CA9 | |
| SCHEMBL4663926 | 0.87 | CA1 (0.53) | CA1CA2EIF2AK2CA12CA9 | |
| SCHEMBL4664315 | 0.87 | CA1 (0.69) | CA1CA2EIF2AK2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009738-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2004-05-19 | — | — | EP | claimed |
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |