Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744504 | 1.00 | ENPP2 (0.46) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL13744450 | 0.96 | ENPP2 (0.46) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL14499145 | 0.95 | ENPP2 (0.44) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL13744512 | 0.94 | ENPP2 (0.45) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL13744578 | 0.89 | PHLPP2 (0.44) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL17384282 | 0.80 | ENPP2 (0.46) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL15985943 | 0.79 | ENPP2 (0.43) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL14388952 | 0.79 | ENPP2 (0.43) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL13196221 | 0.79 | ENPP2 (0.45) | ENPP2PHLPP2SUMO2SUMO1SENP7 | |
| SCHEMBL18652606 | 0.78 | ENPP2 (0.38) | ENPP2PHLPP2PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250575-A1 | Fibre-Reactive Dyes, Their Preparation And Their Use | HUNTSMAN INTERNATIONAL LLC | 2008-10-16 | — | — | US | disclosed |