Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.73 |
| ▸ | FLT1 | P17948 | 1/20 | 0.73 |
| ▸ | FLT4 | P35916 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14148538 | 0.85 | TP53 (0.57) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL7982509 | 0.84 | KDR (0.52) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148536 | 0.82 | KDR (0.49) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148552 | 0.82 | KDR (0.49) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL7744191 | 0.81 | KDR (0.48) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148568 | 0.80 | TP53 (0.54) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148561 | 0.79 | TP53 (0.50) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148571 | 0.79 | KDR (0.62) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148542 | 0.79 | IKBKB (0.48) | KDRFLT1FLT4MEN1KMT2A | |
| SCHEMBL14148540 | 0.79 | TP53 (0.53) | KDRFLT1FLT4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |