Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403952 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL9540328 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL1403964 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL11361072 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL1404140 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL11478314 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL1403975 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL11469686 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL1404117 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL11469082 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291349-A2 | SMALL MOLECULE INHIBITORS OF THE PLECKSTRIN HOMOLOGY DOMAIN AND METHODS FOR USING SAME | The Board of Regents of The University of Texas System (US) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009129267-A2 | SMALL MOLECULE INHIBITORS OF THE PLECKSTRIN HOMOLOGY DOMAIN AND METHODS FOR USING SAME | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-10-22 | — | — | WO | disclosed |
| EP-0354549-A2 | Silver halide photographic lightsensitive material containing novel cyan coupler | KONICA CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |
| US-4476034-A | BLEND OF CHLORINATED PARAFFIN SULFONATE, CARBOXYLATED SULFONAMIDE, POLYOXYALKYLENE GLYCOL AND CARBOXYLATED ETHANOLAMINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-09 | — | — | US | disclosed |