Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108755 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7110016 | 0.87 | SMN1; SMN2 (0.61) | ALDH1A1CYP2C9SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31544568 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4ECYP1A2CYP3A4HPGD | |
| SCHEMBL4768446 | 0.86 | ALDH1A1 (0.74) | ALDH1A1KDM4ECYP1A2CYP3A4HPGD | |
| SCHEMBL14040903 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14502540 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1514453 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4452821 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1KDM4ECYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL8125018 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL934289 | 0.75 | KMT2A (0.56) | ALDH1A1HPGDMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539693-B9 | CANNABINOID RECEPTOR AGONISTS | SCHERING CORP (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1539693-B1 | CANNABINOID RECEPTOR AGONISTS | SCHERING CORP (US) | 2008-03-12 | — | — | EP | disclosed |
| US-7217732-B2 | Cannabinoid receptor agonists | SCHERING CORPORATION (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217732-B2 | Cannabinoid receptor agonists | SCHERING CORPORATION (US) | 2007-05-15 | — | — | US | disclosed |