Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523000 | 0.90 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL3390015 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL3392756 | 0.89 | ALDH1A1 (0.55) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL4302786 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL22716682 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL18425295 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL14043004 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL31197470 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL4648329 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTNPC1MAPK1HTT | |
| SCHEMBL22716841 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |