Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953523 | 0.91 | GSK3B (0.61) | GSK3BCDK2CCNA2CCNA1CHRNA7 | |
| SCHEMBL14050764 | 0.86 | GSK3B (0.53) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL14050762 | 0.84 | GSK3B (0.54) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL12953665 | 0.82 | GSK3B (0.63) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL13305401 | 0.81 | GSK3B (0.56) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL13305326 | 0.81 | GSK3B (0.56) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL14050760 | 0.81 | GSK3B (0.51) | GSK3BCDK2CCNA2CCNA1CHRNA7 | |
| SCHEMBL14050780 | 0.81 | GSK3B (0.60) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL14050761 | 0.81 | GSK3B (0.55) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL12953752 | 0.80 | GSK3B (0.47) | GSK3BCDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |