Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.56 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385560 | 1.00 | ADORA2A (0.75) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12952375 | 0.92 | ADORA2A (0.65) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12118176 | 0.92 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12010026 | 0.92 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12010005 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL10459363 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL10089239 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12952377 | 0.91 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12952076 | 0.91 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1HSP90B1 | |
| SCHEMBL12009904 | 0.91 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124150-A1 | METHOD OF TREATING ENTERITIS, INTESTINAL DAMAGE, AND DIARRHEA FROM C. DIFFICILE WITH AN A2A ADENOSINE RECEPTOR AGONIST | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-10-16 | — | — | WO | disclosed |