Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.60 |
| ▸ | CDK2 | P24941 | 7/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954291 | 0.78 | GSK3B (0.63) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL14050772 | 0.77 | CDK2 (0.49) | GSK3BCDK2 | |
| SCHEMBL12952914 | 0.75 | GSK3B (1.00) | GSK3BCDK2 | |
| SCHEMBL12953472 | 0.75 | GSK3B (0.70) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL13116953 | 0.74 | GSK3B (0.67) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL11930866 | 0.74 | GSK3B (0.63) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL12952999 | 0.73 | GSK3B (0.68) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL13305294 | 0.72 | GSK3B (0.71) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL12954279 | 0.72 | GSK3B (0.71) | GSK3BCDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL12952905 | 0.71 | GSK3B (0.65) | GSK3BCDK2CHEK1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |