Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.49 |
| ▸ | GSK3B | P49841 | 13/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043386 | 0.77 | GSK3B (0.60) | CDK2GSK3B | |
| SCHEMBL14545201 | 0.69 | CDK2 (0.43) | CDK2GSK3B | |
| SCHEMBL12953562 | 0.68 | CDK2 (0.43) | CDK2GSK3B | |
| SCHEMBL13118130 | 0.63 | CDK2 (0.69) | CDK2GSK3B | |
| SCHEMBL12953996 | 0.63 | GSK3B (1.00) | CDK2GSK3B | |
| SCHEMBL14545802 | 0.63 | CDK2 (0.51) | CDK2GSK3B | |
| SCHEMBL15381337 | 0.62 | GSK3B (0.71) | CDK2GSK3B | |
| SCHEMBL12953193 | 0.62 | GSK3B (1.00) | CDK2GSK3B | |
| SCHEMBL14050847 | 0.62 | GSK3B (0.74) | CDK2GSK3B | |
| SCHEMBL13305163 | 0.61 | GSK3B (0.75) | CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130569-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |