Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.76 |
| ▸ | BCR | P11274 | 16/20 | 0.76 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.76 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.76 |
| ▸ | SRC | P12931 | 8/20 | 0.74 |
| ▸ | PRKCA | P17252 | 6/20 | 0.74 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.74 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.74 |
| ▸ | PRKCG | P05129 | 1/20 | 0.74 |
| ▸ | PRKCB | P05771 | 1/20 | 0.74 |
| ▸ | PRKCH | P24723 | 1/20 | 0.74 |
| ▸ | PRKCI | P41743 | 1/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.74 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.74 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.74 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.74 |
| ▸ | ABL2 | P42684 | 2/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | SYK | P43405 | 1/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904803 | 0.92 | ABL1 (0.66) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL4903651 | 0.92 | ABL1 (0.64) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL4892458 | 0.88 | PDGFRA (0.78) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4901151 | 0.88 | ABL1 (0.80) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL6041110 | 0.87 | ABL1 (0.57) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL9565 | 0.86 | ABL1 (1.00) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL1430 | 0.85 | ABL1 (1.00) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL9197 | 0.85 | ABL1 (1.00) | ABL1BCRPDGFRBPDGFRASRC | |
| SCHEMBL1653882 | 0.85 | ABL1 (0.70) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL10208 | 0.84 | ABL1 (0.82) | ABL1BCRPDGFRBPDGFRASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130944-A1 | SOLID PHASE SYNTHESES OF AMINO PYRIMIDINE COMPOUNDS | IRM LLC (BM) | 2008-10-30 | — | — | WO | disclosed |