Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | BCR | P11274 | 9/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | PRKCA | P17252 | 5/20 | 0.60 |
| ▸ | SRC | P12931 | 3/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | PRKCG | P05129 | 1/20 | 0.60 |
| ▸ | PRKCB | P05771 | 1/20 | 0.60 |
| ▸ | PRKCH | P24723 | 1/20 | 0.60 |
| ▸ | PRKCI | P41743 | 1/20 | 0.60 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.60 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.60 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.60 |
| ▸ | ABL2 | P42684 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043504 | 0.92 | ABL1 (0.76) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4892458 | 0.89 | PDGFRA (0.78) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL4897346 | 0.87 | ABL1 (0.67) | ABL1BCRPDGFRBPDGFRAHDAC1 | |
| SCHEMBL4897416 | 0.85 | TRPV1 (0.53) | ABL1 | |
| SCHEMBL4903275 | 0.84 | ABL1 (0.81) | ABL1BCRPDGFRBPDGFRAHDAC1 | |
| SCHEMBL4903136 | 0.83 | PDGFRA (0.82) | ABL1BCRPDGFRBPDGFRAHDAC1 | |
| SCHEMBL4905733 | 0.83 | PDGFRA (0.77) | ABL1BCRPDGFRBPDGFRAHDAC1 | |
| SCHEMBL4901659 | 0.83 | ABL1 (0.81) | ABL1BCRPDGFRBPDGFRAHDAC1 | |
| SCHEMBL4904803 | 0.83 | ABL1 (0.66) | ABL1BCRPDGFRBPDGFRAPRKCA | |
| SCHEMBL3863391 | 0.81 | PDGFRA (0.78) | ABL1BCRPDGFRBPDGFRAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | claimed |
| EP-1786781-A2 | PYRIMIDINE DERIVATIVES | GPC Biotech AG (DE) | 2007-05-23 | — | — | EP | claimed |
| WO-2006021458-A2 | PYRIMIDINE DERIVATIVES | GPC BIOTECH AG (DE) | 2006-03-02 | — | — | WO | claimed |
| US-20080187575-A1 | Pyrimidine Derivatives | VICHEM CHEMIE KFT (HU) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187575-A1 | Pyrimidine Derivatives | TYMP, TDP1, PNP | ABL1 2843/4885OPRM1 3721/4885KCNH2 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.