Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711030 | 0.84 | HDAC8 (0.59) | MEN1ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL14044001 | 0.82 | FFAR1 (0.79) | FFAR1NR4A2TSHRSMN1; SMN2RAB9A | |
| SCHEMBL14043995 | 0.79 | MAPT (0.76) | FFAR1NR4A2TSHRSMN1; SMN2RAB9A | |
| SCHEMBL4355854 | 0.79 | MEN1 (0.60) | FFAR1RAB9AMEN1ALDH1A1MAPT | |
| SCHEMBL4346825 | 0.78 | MEN1 (0.62) | FFAR1SMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL14044005 | 0.78 | FFAR1 (0.70) | FFAR1NR4A2TSHRSMN1; SMN2RAB9A | |
| SCHEMBL14043999 | 0.78 | FFAR1 (0.65) | FFAR1NR4A2TSHRSMN1; SMN2RAB9A | |
| SCHEMBL4745955 | 0.77 | FFAR1 (0.61) | FFAR1TSHRSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL14043656 | 0.77 | NR4A2 (0.69) | FFAR1NR4A2TSHRSMN1; SMN2RAB9A | |
| SCHEMBL1122713 | 0.77 | NR4A2 (0.94) | FFAR1NR4A2TSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |