Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 0.94 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.76 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 1/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.68 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.68 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339009 | 0.97 | NR4A2 (1.00) | NR4A2MRGPRX4SRD5A2MAOBNR1H4 | |
| SCHEMBL30207018 | 0.97 | NR4A2 (1.00) | NR4A2MRGPRX4SRD5A2MAOBNR1H4 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.95 | NR4A2 (0.97) | NR4A2MRGPRX4SRD5A2MAOBNR1H4 | |
| SCHEMBL4406160 | 0.93 | NR4A2 (0.87) | NR4A2MRGPRX4SRD5A2SMN1; SMN2 | |
| SCHEMBL1123155 | 0.92 | NR4A2 (0.91) | NR4A2MRGPRX4SRD5A2MAOBNR1H4 | |
| SCHEMBL4138759 | 0.90 | NR4A2 (0.81) | NR4A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL1123461 | 0.89 | NR4A2 (0.81) | NR4A2MRGPRX4SRD5A2FFAR1MEN1 | |
| SCHEMBL27655015 | 0.88 | NR4A2 (0.72) | NR4A2MRGPRX4SMN1; SMN2 | |
| SCHEMBL30994900 | 0.87 | NR4A2 (0.82) | NR4A2MRGPRX4SRD5A2MAOBNR1H4 | |
| SCHEMBL27815839 | 0.87 | NR4A2 (0.82) | NR4A2MRGPRX4SRD5A2MAOBNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | NR4A2 66/4885MRGPRX4 1739/4885SRD5A2 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.