Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262049 | 0.86 | CA1 (0.72) | MEN1KMT2ACA1CA2HIF1A | |
| SCHEMBL14044007 | 0.86 | FFAR1 (0.69) | FFAR1FFAR4CA1CA2HIF1A | |
| SCHEMBL6258120 | 0.85 | FFAR1 (0.49) | MEN1KMT2AFFAR1FFAR4CA1 | |
| SCHEMBL6260082 | 0.84 | TSHR (0.58) | FFAR1ALDH1A1ADRB2 | |
| SCHEMBL1446643 | 0.82 | CA1 (0.70) | FFAR1FFAR4CA1CA2HIF1A | |
| SCHEMBL14043636 | 0.82 | HIF1A (0.62) | FFAR1FFAR4CA1CA2HIF1A | |
| SCHEMBL5273870 | 0.80 | HIF1A (0.69) | MEN1KMT2ACA1CA2SYK | |
| SCHEMBL11259354 | 0.79 | L3MBTL1 (0.63) | FFAR1FFAR4CA1CA2SYK | |
| SCHEMBL11248559 | 0.78 | KMT2A (0.50) | MEN1KMT2ACA1CA2HIF1A | |
| SCHEMBL20897517 | 0.78 | CYP1A2 (0.51) | MEN1KMT2AFFAR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |