Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 18/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 17/20 | 0.39 |
| ▸ | PGR | P06401 | 12/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228290 | 0.89 | NR3C1 (0.49) | NR3C2NR3C1PGR | |
| SCHEMBL14044318 | 0.87 | NR3C2 (0.40) | NR3C2NR3C1PGR | |
| SCHEMBL14044111 | 0.79 | NR3C1 (0.50) | NR3C2NR3C1PGR | |
| SCHEMBL3222268 | 0.77 | NR3C1 (0.56) | NR3C2NR3C1PGR | |
| SCHEMBL3219833 | 0.75 | NR3C2 (0.52) | NR3C2NR3C1PGR | |
| SCHEMBL3227066 | 0.72 | NR3C1 (0.52) | NR3C2NR3C1PGR | |
| SCHEMBL3223020 | 0.71 | NR3C1 (0.59) | NR3C2NR3C1PGR | |
| SCHEMBL3226410 | 0.71 | NR3C1 (0.50) | NR3C2NR3C1PGR | |
| SCHEMBL3218042 | 0.71 | NR3C2 (0.50) | NR3C2NR3C1PGR | |
| SCHEMBL14044319 | 0.69 | NR3C1 (0.40) | NR3C2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |