Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 17/20 | 0.50 |
| ▸ | PGR | P06401 | 13/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CCR10 | P46092 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213859 | 0.87 | NR3C1 (0.54) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3220259 | 0.76 | NR3C1 (0.59) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL13493343 | 0.76 | NR3C1 (0.59) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3203485 | 0.73 | NR3C1 (0.52) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3222412 | 0.69 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL3203290 | 0.68 | NR3C1 (0.47) | NR3C1NR3C2PGRCYP3A4CCR10 | |
| SCHEMBL3643264 | 0.67 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4CCR10 | |
| SCHEMBL3767289 | 0.67 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4CCR10 | |
| SCHEMBL4551721 | 0.65 | NR3C1 (0.52) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3260372 | 0.65 | NR3C1 (0.49) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |