Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 18/20 | 0.52 |
| ▸ | PGR | P06401 | 13/20 | 0.52 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222767 | 0.90 | NR3C2 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL14044317 | 0.82 | NR3C1 (0.56) | NR3C1NR3C2PGR | |
| SCHEMBL3213239 | 0.82 | NR3C2 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL3227428 | 0.81 | NR3C1 (0.62) | NR3C1NR3C2PGR | |
| SCHEMBL3220519 | 0.78 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL3218295 | 0.76 | NR3C2 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL3228096 | 0.75 | NR3C2 (0.70) | NR3C1NR3C2PGR | |
| SCHEMBL3223164 | 0.75 | NR3C1 (0.77) | NR3C1NR3C2PGR | |
| SCHEMBL3223175 | 0.74 | NR3C1 (0.65) | NR3C1NR3C2PGR | |
| SCHEMBL3219789 | 0.74 | NR3C1 (0.71) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |