Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810931 | 0.87 | MET (0.51) | MET | |
| SCHEMBL4817737 | 0.84 | MET (0.49) | MET | |
| SCHEMBL4818945 | 0.78 | MET (0.74) | MET | |
| SCHEMBL4816753 | 0.77 | MET (0.64) | MET | |
| SCHEMBL4047358 | 0.69 | MET (0.47) | MET | |
| SCHEMBL4819671 | 0.67 | KDR (0.57) | MET | |
| SCHEMBL4390517 | 0.67 | MET (0.57) | MET | |
| SCHEMBL5408778 | 0.67 | MET (0.43) | MET | |
| SCHEMBL4814662 | 0.66 | MET (0.55) | MET | |
| SCHEMBL4812536 | 0.65 | MET (1.00) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439246-B2 | Fused heterocyclic kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| US-7432373-B2 | Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors | BRISTOL-MEYERS SQUIBB COMPANY (US) | 2008-10-07 | — | — | US | disclosed |