Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14045448 | 0.96 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2GPBAR1ALDH1A1MAPT | |
| SCHEMBL4889143 | 0.89 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1ALDH1A1MAPT | |
| SCHEMBL4856376 | 0.87 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4841922 | 0.85 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1ALDH1A1MAPT | |
| SCHEMBL14045446 | 0.83 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2GPBAR1ALDH1A1MAPT | |
| SCHEMBL14045450 | 0.81 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14045447 | 0.80 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4841879 | 0.80 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2GPBAR1ALDH1A1MAPT | |
| SCHEMBL4841446 | 0.79 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL4849551 | 0.78 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |